Profile of Lecturer
Download Powerpoint version of this lecture
Click images to enlarge
|
Pneumococcal disease: meningitis
|
|
|
Pneumococcal disease
S. pneumoniae is the leading cause
of bacterial meningitis in elderly persons. This study involved the surveillance of a
population of 34 million people in the USA in 1986.
S. pneumoniae was the cause of
nearly 40% of cases of meningitis among the 30 59 year old group, and of nearly 50%
of the cases among elderly patients (aged > 60 years).
In western countries (where Hib
vaccination programmes have been implemented for several years), S. pneumoniae is
the most common cause of bacterial meningitis.
|
|
Epidemiology: invasive pneumococcal disease
Where vaccination programmes against Haemophilus
influenzae type b (Hib) have been implemented, S. pneumoniae is now the most
common cause of bacterial meningitis.
The case fatality rate for pneumococcal
meningitis is high, particularly among adults.
|
|
Pneumococcal disease: medical management
Treatment usually begins before the
aetiology of the disease is known. The choice of therapy should be governed by knowledge
of local patterns of resistance.
Oral amoxycillin is often used to treat
pneumonia in patients treated in the community. Hospitalised patients often receive
multiple antibiotics administered intravenously (e.g. cephalosporin + erythromycin)
Because of antibiotic resistance,
penicillin is also no longer the first line of treatment for suspected pneumococcal
meningitis. A third-generation cephalosporin is often used now.
|
|
<<previous
1
2
3
4
5
6
next>>
|